The actress, who stars alongside Demi Moore in the body horror film, says it took "probably a year" for her skin to recover.

Margaret Qualley is opening up about the long-lasting effects she suffered while filming for 'The Substance.' The actress, who plays Sue in the body horror film, recently shared on the Happy Sad Confused podcast that her skin was damaged for nearly a year after filming wrapped.

The actress recalled what it was like working with prosthetics for her role in the body horror film, which also stars Demi Moore.

Adhesive materials, artificial skin, and layers of heavy makeup used to create these effects can often clog pores

Qualley stars in the film opposite Demi Moore, who plays an aging film star Elisabeth Sparkle. Sparkle takes the "substance" in order to transform into Sue (Qualley) but there's a catch: the pair must switch back every seven days. If they don't, Sue will begin deteriorating (and, it turns out, so will Sparkle).

"It took me probably, like, a year to recover physically from all of it," she told a podcast about the prosthetics used in the film.

During a recent appearance on the Happy Sad Confused podcast, Margaret Qualley revealed that the prosthetics she wore in "The Substance" "f--ked up" her skin, saying that it took "a year" for her skin to fully recover from the acne.

The actress spoke about dealing with acne caused by the movie makeup on Josh Horowitz's 'Happy Sad Confused' podcast