Rubio began his trip in Panama, where he attended Mass at Our Lady of Mercy in Panama City. Talks swiftly pivoted to U.S.

President José Mulino said Panama's sovereignty over the world's second busiest waterway is not up for discussion.

The State Department claimed it had struck a deal that would save the U.S. government “millions of dollars a year.” ...

This is a collection of photos chosen by AP photo editors.

U.S. Secretary of State Marco Rubio, on his first foreign trip as America's top diplomat, held face-to-face talks with Mulino ...

The Korn Ferry Tour closes January with the 21st Panama Championship at the historic Club de Golf de Panama in Panama City, Panama. The tournament is set to showcase an impressive field of Korn ...

Rubio toured the trans-continental passage during a multi-stop journey in South America, celebrating Panama's withdrawal from ...

Lionel Messi is expected to play as Inter Miami faces Sporting San Miguelito in Panama City, Panama at 5 p.m. ET. Here's what ...

PANAMA CITY — U.S. Secretary of State Marco Rubio ... Rubio later planned to tour the canal, Mulino said he hoped Rubio’s visit would focus on shared interests such as migration and combating ...

Marco Rubio delivered a stark warning to Panama's president on February 2 that Washington would 'take measures necessary' if ...

From white-sand beaches to lakefront views and even a riverwalk filled with shopping and dining, these five Southern ...

Security cooperation, migration issues were a focus on previous stops in Panama, El Salvador, Costa Rica and Guatemala ...